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HelpTest Code CTDC Connective Tissue Disease Cascade
EHR Test Codes
| Test Code | Test Name | |
| Atlas | CTDC | Connective Tissue Diseases Cascade, Serum |
| Cerner | Connective Tissue Disease Cascade |
Specimen Requirements
Preparation of Patient:
None
Container Type:
Gold Top 6mL SST Gel & Clot Activator Tube
Specimen Type:
Serum
Specimen Volume:
5 mL Serum minimum 2.5 mL
Specimen Handling/Transport:
Separate serum from cells within 2 hours of collection.
Transport ambient room temperature or refrigerated 2 - 8°C.
Specimen Stability/Storage:
< 8 hours ambient room temperature, 2 days 2 - 8°C, > 7 days -20°C
Performing Laboratory
Munson Medical Center Laboratories
Microbiology Department
When indicated ENAE and RIB are referred to Mayo Diagnostic Laboratory.
Priority, Frequency, Turnaround Time
Priority:
Non-Emergent
Frequency:
Monday - Friday
Batch testing run 1 - 2 times per week, variable days.
Turnaround:
0 - 7 days
Test Panel
Algorithm: Connective Tissue Disease Cascade
| CCP | Cyclic Citrullinated Peptide | Always Performed |
| ANA | Antinuclear Antibody | Always Performed |
| ENAE | Extractable Nulear Antigen Antibodies | If ANA is positive |
| RIB | Ribosome P Antibodies | If ANA is positive |
| DSDNA | Double Stranded DNA | If ANA homogeneous pattern |
Methodology
See individual tests for more informaiton
Reporting
Reference Range:
Negative
Interpretation:
See individual tests for more information.
Critical Decision:
None
Clinical Significance
Aide in the diagnosis of connective tissue diseases such as, Rheumatoid Arthritis (RA), Lupus Erythematosus (LE) with or without potential CNS involvement, Sjogren Syndrome, Mixed Connective Tissue Disease, Scleroderma, and Polymyositis. See individual tests for more information.
CPT Code(s)
86201 - CCP Cyclic Citrullinated Antibody IgG
86038 - ANA Antinuclear Antibody
If reflex tests performed:
86039 - Antinuclear Antibody Titer and Pattern
86235x6 - ENAE Extractable Nuclear Antigen Antibodies
83516 - RIB Ribosome P Antibodies