Test Code DSDNA Double Stranded DNA IgG
EHR Test Codes
| Test Code | Test Name | |
| Atlas | ADNA | Anti dsDNA |
| Cerner | Double Stranded DNA IgG |
Specimen Requirements
Preparation of Patient:
None
Container Type:
Gold Top 6mL SST Gel & Clot Activator Tube
Specimen Type:
Serum
Specimen Volume:
2.5 mL Serum minimum .5 mL
Specimen Handling/Transport:
Transport ambient room temperature.
Specimen Stability/Storage:
2 days 2 - 8°C, > 7 days -20°C
Performing Laboratory
Munson Medical Center Laboratories
Microbiology Department
Priority, Frequency, & Turnaround
Priority:
Non-Emergent
Frequency:
Monday - Friday
Turnaround:
0 - 3 days
Methodology
Indirect Immunoflourescent Assay using Crithidia luciliae Hemoflagellate
Reporting
Reference Range:
Negative
If positive, titer is performed.
Critical Decision:
None
Clinical Significance
While the commonly used Anti-nuclear Antibody (ANA) test is a sensitive screening test for SLE and other connective tissue diseases, it is by no means specific for SLE. Because of this, all positive ANA homogeneous samples should be tested for specific antibodies to dsDNA. The presence of antibodies to dsDNA strongly indicates SLE; however, absence of these antibodies does not rule out SLE in all cases
CPT Code(s)
86225