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Test Code DSDNA Double Stranded DNA IgG

EHR Test Codes

  Test Code Test Name
Atlas ADNA Anti dsDNA
Cerner   Double Stranded DNA IgG

Specimen Requirements

Preparation of Patient: 

None

 

Container Type: 

Gold Top 6mL SST Gel & Clot Activator Tube

Specimen Type:

Serum

 

Specimen Volume: 

2.5 mL Serum minimum .5 mL

 

Specimen Handling/Transport:

Transport ambient room temperature.

 

Specimen Stability/Storage:

 2 days 2 - 8°C, > 7 days -20°C

Performing Laboratory

Munson Medical Center Laboratories

Microbiology Department

Priority, Frequency, & Turnaround

Priority:

Non-Emergent

 

Frequency:

Monday - Friday

 

Turnaround:

0 - 3 days

Methodology

Indirect Immunoflourescent Assay using Crithidia luciliae Hemoflagellate

Reporting

Reference Range:

Negative

If positive, titer is performed.

 

Critical Decision: 

None

Clinical Significance

While the commonly used Anti-nuclear Antibody (ANA) test is a sensitive screening test for SLE and other connective tissue diseases, it is by no means specific for SLE. Because of this, all positive ANA homogeneous samples should be tested for specific antibodies to dsDNA. The presence of antibodies to dsDNA strongly indicates SLE; however, absence of these antibodies does not rule out SLE in all cases

CPT Code(s)

86225