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Test Code CCP Cyclic Citrullinated Peptide IgG

EHR Test Codes

  Test Code Test Name
Atlas CCP Cyclic Citrullinated Peptide IgG
Cerner   Cyclic Citrullinated Peptide IgG

Specimen Requirements

Preparation of Patient: 

None

 

Container Type: 

Gold Top 6mL SST Gel & Clot Activator Tube

Specimen Type:

Serum

 

Specimen Volume: 

2.5 mL Serum minimum .5 mL

 

Specimen Handling/Transport:

Separate serum from cells within 2 hours of collection.

Transport ambient room temperature or refrigerated 2 - 8°C.

 

Specimen Stability/Storage:

 < 8 hours ambient room temperature, 2 days 2 - 8°C, > 7 days -20°C

 

Performing Laboratory

Munson Medical Center Laboratories

Microbiology Department

Priority, Frequency, & Turnaround

Priority:

Non-Emergent

 

Frequency:

Monday - Friday

Batch testing run 1 - 2 times per week, variable days.

 

Turnaround:

0 - 7 days

Methodology

Enzyme Immunoassay

Reporting

Reference Range:

Negative

 

Interpretation:

Units   Result Interpretation
< 20 Negative A negative result indicates no CCP 3 antibodies or levels below the negative cut-off of the assay.
20 - 39 Weak Positive Presence of IgG and/or IgA anti-CCP 3 antibodies and suggests the possibility of RA
40 - 59 Moderate Positive
> 60 Strong Positive

 

Critical Decision: 

None

Clinical Significance

Rheumatoid Arthritis (RA) is one of the most common systemic autoimmune diseases, affecting approximately 0.5% of the world population. The diagnosis depends primarily on clinical manifestations of the disease. Until recently, the only serological test routinely used was the determination of the presence of rheumatoid factor (RF), found in approximately 50%-90% of these patients. However, RF is also found in people with infections, other autoimmune diseases and some healthy individuals.

CPT Code(s)

86201