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Test Code HBCTD Hepatitis B Core Antibody Total IgG and IgM

EHR Test Codes

  Test Code Test Name
Atlas HBCTD Hepatitis B Core Ab Total, Serum
Cerner   Hepatitis B Core Antibody Total IgG and IgM

 

Specimen Requirements

Preparation of Patient: 

None

 

Container Type: 

Gold Top 6mL SST Gel & Clot Activator Tube

Specimen Type:

Serum

 

Specimen Volume: 

2.5 mL Serum minimum .5 mL

 

Specimen Handling/Transport:

Separate serum  from cells within 2 hours of collection.

Transport ambient room temperature or refrigerated 2 - 8°C

 

Specimen Stability/Storage:

4 days ambient room temperature

4 days refrigerated 2-8°C

 

Specimen Rejection:

Gross Hemolysis

Gross Lipemia

Performing Laboratory

Munson Medical Center Laboratories

Chemistry Department

Priority, Frequency, & Turnaround

Priority:

Non-Emergent

 

Frequency:

Monday - Friday

 

Turnaround:

0 - 3 days

Methodology

Chemiluminometric Immunoassay

Reporting

Reference Range:

Negative

 

Result Interpretation:

  • Index ≥1.10 are NEGATIVE
  • Index <0.900 are POSITIVE
  • Index values 0.900 to 1.10 are initially equivocal. Sample must be retested in duplicate. If 2/3 results are ≥1.00 result is NEGATIVE. If 2/3 are <1.00 result is POSITIVE

 

Critical Decision:

None

 

Clinical Significance

Total hepatitis B core antibodies IgG and IgM (Anti-HBc Total) appear at the onset of symptoms and persist for life.  The presence of Anti-HBc Total indicates previous or ongoing infection with Hepatitis B Virus (HBV) in an undefined time frame.  It may be the only detectable marker during the period when HBsAg ends and Anti-HBs appears.  People who have immunity to hepatitis B from a vaccine do not develop Anti-HBc.  

 

Different serologic markers or combinations of markers are used to identify different phases of HBV infection. They determine whether a patient has acute or chronic HBV infection, is immune to HBV as a result of prior infection or vaccination, or is susceptible to infection. Markers include:  HBsAg, Anti-HBs, Anti-HBc Total (IgM & IgM) and Anti-HBc IgM.  It is recommened that Hepatitis B Screening be performed in a triple panel; HBsAg, Anti-HBs, and Anti-HBc Total.

CPT Code(s)

86704

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