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Test Code HBCMD Hepatitis B Core Antibody IgM

EHR Test Codes

  Test Code Test Name
Atlas HBCMD Hepatitis B Core Ab IgM, Serum
Cerner   Hepatitis B Core Antibody IgM

 

Specimen Requirements

Preparation of Patient: 

None

 

Container Type: 

Gold Top 6mL SST Gel & Clot Activator Tube

Specimen Type:

Serum

 

Specimen Volume: 

2.5 mL Serum minimum .5 mL

 

Specimen Handling/Transport:

Separate serum  from cells within 2 hours of collection.

Transport ambient room temperature or refrigerated 2 - 8°C

 

Specimen Stability/Storage:

4 days ambient room temperature

5 days refrigerated 2-8°C

 

Specimen Rejection:

Gross Hemolysis

Gross Lipemia

Performing Laboratory

Munson Medical Center Laboratories

Chemistry Department

Priority, Frequency, & Turnaround

Priority:

Non-Emergent

 

Frequency:

Monday - Friday

 

Turnaround:

0 - 3 days

Methodology

Chemiluminometric Immunoassay

Reporting

Reference Range:

Negative

 

Result Interpretation:

  • Index ≥0.900 are reported as POSITIVE
  • Index <0.700 are reported as NEGATIVE
  • Index ≥0.700 and <0.900 are considered EQUIVOCAL and must be repeated in duplicate. If 2/3 are ≥0.800 the sample is reported as POSITIVE. If 2/3 are <0.800 the sample is reported as NEGATIVE

 

Critical Decision:

None

 

Clinical Significance

Hepatitis B core antibody IgM (Anti-HBc IgM) appear at the onset of symptoms and indicates acute infection with Hepatitis B Virus (HBV).  It may be the only detectable marker during the period when HBsAg ends and Anti-HBs appears.  Anti-HBc IgM may also be positive during flares or reactivation of chronic infection with HBV.

 

Different serologic markers or combinations of markers are used to identify different phases of HBV infection. They determine whether a patient has acute or chronic HBV infection, is immune to HBV as a result of prior infection or vaccination, or is susceptible to infection. Markers include:  HBsAg, Anti-HBs, Anti-HBc Total (IgM & IgM) and Anti-HBc IgM.  It is recommened that Hepatitis B Screening be performed in a triple panel; HBsAg, Anti-HBs, and Anti-HBc Total.  Anti-HBc IgM should be ordered only when acute HBV infection is a concern.

CPT Code(s)

86704

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