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Test Code BSABD Hepatitis B Surface Antibody

EHR Test Codes

  Test Code Test Name
Atlas BSABD Hepatitis B Surface Antibody QL/QN
Cerner   Hepatitis B Surface Antibody

 

Specimen Requirements

Preparation of Patient: 

None

 

Container Type: 

Gold Top 6mL SST Gel & Clot Activator Tube

Specimen Type:

Serum

 

Specimen Volume: 

2.5 mL Serum minimum .5 mL

 

Specimen Handling/Transport:

Separate serum  from cells within 2 hours of collection.

Transport ambient room temperature or refrigerated 2 - 8°C

 

Specimen Stability/Storage:

1 day ambient room temperature

5 days refrigerated 2-8°C

 

Specimen Rejection:

Gross Hemolysis

Gross Lipemia

Performing Laboratory

Munson Medical Center Laboratories

Chemistry Department

Priority, Frequency, & Turnaround

Priority:

Non-Emergent

 

Frequency:

Monday - Friday

 

Turnaround:

0 - 3 days

Methodology

Chemiluminometric Immunoassay

Reporting

Reference Range:

Negative

< 9.9 mIU/mL

 

Interpretation:

  • Index < 10.0 mIU/mL are considered NEGATIVE for Anti-HBs.  Individual is considered to be not immue to infection with HBV
  • Index ≥ 11.0 mIU/mLare considered POSITIVE for Anti-HBs.  Individual is considered to be immune to infection with HBV
  • Index ≥ 9.0 - < 11.0 mIU/mL are considered EQUIVOCAL and must be repeated in duplicate.  Samples which are Equivocal on 2 of the 3 replicates < 10 mIU/mL should be reported as NEGATIVE and 2 of the 3 replicates ≥ 10 mIU/mL should be reported as POSITIVE.

 

Critical Decision:

None

Clinical Significance

Detection of anti-HBs is critical in establishing whether complete resolution of the infection has occurred as well as in establishing the acquisition of immunity, whether acquired as a result of natural HBV infection or vaccination.

 

Hepatitis B is a liver infection caused by the hepatitis B virus (HBV).  Diagnosis of HBV infection is achieved through blood or serum detection of viral nucleic acid or serological markers.  Common HBV serological markers include Hepatitis B surface Antigen (HBsAg), Hepatitis B surface Antibody (anti-HBs), total antibody to hepatitis B core antigen (HBcAg) (total anti-HBc), immunoglobulin M (IgM) antibody to HBcAg (IgM anti-HBc), hepatitis B e antigen (HBeAg), and antibody to HBeAg (anti-HBe).  The detection of these serological markers allows identification of past or ongoing HBV infection, assessment of the clinical phases of the disease, monitoring of antiviral therapy and determination of the immune status of the patient.

CPT Code(s)

86706