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Test Code TSHS Thyroid Stimulating Hormone 

Important Note

Medicare frequency limitations exist for this test in addition to diagnosis requirements. Click on link for list of medically necessary diagnoses: http://www.munsonhealthcare.org/medical-necessity. Click on link for Advance Beneficiary Notice of Noncoverage form: Advance Beneficiary Notice of Noncoverage

EHR Test Codes

  Test Code Test Name
Atlas TSHS TSH, Sensitivity
Cerner TSH Thyroid Stimulating Hormone

Specimen Requirements

Preparation of Patient: 

None

 

Container Type: 

Green Top 5mL Lithium Heparin Separator Tube

Or

 

Gold Top 6mL SST Gel & Clot Activator Tube

Specimen Type:

Plasma or Serum

 

Specimen Volume: 

2.5 mL Plasma or Serum minimum .5 mL

 

Specimen Handling/Transport:

Separate plasma or serum from cells within 2 hours of collection.

Transport ambient room temperature.

 

Specimen Stability/Storage:

5 days refrigerated 2-8°C

Performing Laboratory

Munson Medical Center Laboratories

Chemistry Department

Priority, Frequency, & Turnaround

Priority:

Non-Emergent

 

Frequency:

24 hours 7 days a week

 

Turnaround:

0 - 1 days

Methodology

Chemiluminescence Immunoassay

Reporting

Reference Range:

 0 - 1 month none

> 1 month 0.45 - 5.33 uIU/mL

 

Critical Decision:

None

Clinical Significance

TSH, released from the anterior pituitary, is the principal regulator of thyroid function, stimulating the synthesis and release of thyroid hormones thyroxine (T4) and triiodothyronine (T3). T3 and T4 regulate biochemical processes that are essential for normal metabolism. The synthesis and secretion of TSH is stimulated by thyrotropin-releasing hormone (TRH), which is produced by the hypothalamus in response to low levels of circulating T3 and T4. In contrast, elevated levels of T3 and T4 suppress the production of TSH. Collectively, this negative feedback system is referred to as the hypothalamic-pituitary-thyroid axis. Any alteration in the function of this axis can influence the levels of TSH, T4, and T3 in circulation.

 

The principal clinical use for TSH measurement is for the assessment of thyroid status. TSH is measured in conjunction with thyroid hormones or antibodies to: 1) detect or exclude hypothyroidism or hyperthyroidism; 2) monitor T4 replacement treatment in hypothyroidism or antithyroid treatment in hyperthyroidism and 3) monitor TSH suppression in thyroid cancer patients on thyroxine therapy.

 

Reference ranges for TSH may vary, depending on the method of analysis, and do not necessarily equate to cutoffs for diagnosing thyroid dysfunctio

CPT Code(s)

84443

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