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Test Code PTN Phenytoin Level Total 

EHR Test Codes

  Test Code Test Name
Atlas PTN Phenytoin
Cerner   Phenytoin Level Total 

Specimen Requirements

Preparation of Patient: 

Collect a specimen representing the trough level just before the next dose.  Samples from patients receiving fospheytoin should be drawn at least 2 hours following IV administration and 4 hours following IM administration per the recommendations of the manufacturer. The change in the phenytoin concentration is dependent on the amount of time that has elapsed since the administration of fosphenytoin.

 

Container Type: 

Green Top 5mL Lithium Heparin Separator Tube

Or

 

Gold Top 6mL SST Gel & Clot Activator Tube

Specimen Type:

Plasma or Serum

 

Specimen Volume: 

2.5 mL Plasma or Serum minimum .5 mL

 

Specimen Handling/Transport:

Separate plasma or serum from cells within 2 hours of collection.

Transport refrigerated 2 - 8°C.

 

Specimen Stability/Storage:

5 days refrigerated 2-8°C

Performing Laboratory

Munson Medical Center Laboratories

Chemistry Department

Priority, Frequency, & Turnaround

Priority:

STAT, ASAP, Non-Emergent

 

Frequency:

24 hours 7 days a week

 

Turnaround:

0 - 1 days

STAT 45 minute from receipt in lab

Methodology

Emit 2000 enzyme immunoassay

Reporting

Reference Range:

10 - 20 ug/mL

 

Critical Decision: 

> 30 ug/mL

Note:  Critical values are called to the provider and communicated as critical.  Documentation of the call is recorded in the patient record.

Clinical Significance

Phenytoin is used primarily in the treatment of seizure disorders. It is highly effective in the control of grand mal, focal sensory and motor and psychomotor seizures but of no use in petit mal seizures. Phenytoin is also used in the treatment of cardiac arrhythmias such as ventricular ectopic rhythms and paroxysmal atrial tachycardia due to digitalis toxicity.

 

Common brand names are Dilantin and Phenytek.

CPT Code(s)

80185