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Test Code PSATF Prostate-Specific Antigen (PSA), Total and Free, Serum

Methodology

Immunoenzymatic Assay

Performing Laboratory

Munson Healthcare Laboratories

Specimen Requirements

Specimen must arrive within 24 hours of draw.

 

Container/Tube: Gold-top serum gel tube

Specimen Volume: 0.5 mL of serum
Transport Temperature: Refrigerate
Collection Instructions: Forward promptly.

Note: Medicare frequency limitations exist for this test in addition to diagnosis requirements.  Click on link for list of medically necessary diagnoses: http://www.munsonhealthcare.org/medical-necessity.  See Advance Beneficiary Notice of Noncoverage (ABN) form in Special Instructions.

Reference Values

None available for PSA, free. PSA, free is reported as a percentage of PSA, total, the following reference ranges apply to this ratio:

 

About 25% of asymptomatic men older than 50 years and PSA values of 4.0-10 ng/mL have prostate cancer, compared with about 12% for those with PSA values of 2.0-3.9 ng/mL. Free PSA can help classify these men into subgroups with higher or lower cancer rates:

 

  Free/Total Ratio Cancer Rate
     

PSA 4.0-10 ng/mL

<0.10 >40%
  >0.25 <10%
PSA 2.0-3.9 ng/mL <0.10 >30%
   >0.18  <10%

Serum markers are not specific for malignancy, and values may vary by method.

Day(s) Test Set Up

Monday through Sunday

Test Classification and CPT Coding

84153-PSA, total

84154-PSA, free