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Test Code PSATF Prostate-Specific Antigen (PSA), Total and Free, Serum

Specimen Requirements

Specimen must arrive within 24 hours of draw.

 

Container/Tube: Gold-top serum gel tube

Specimen Volume: 0.5 mL of serum
Transport Temperature: Refrigerate
Collection Instructions: Forward promptly.

Note: Medicare frequency limitations exist for this test in addition to diagnosis requirements.  Click on link for list of medically necessary diagnoses: http://www.munsonhealthcare.org/medical-necessity.  See Advance Beneficiary Notice of Noncoverage (ABN) form in Special Instructions.

Performing Laboratory

Munson Healthcare Laboratories

Methodology

Immunoenzymatic Assay

Reference Values

None available for PSA, free. PSA, free is reported as a percentage of PSA, total, the following reference ranges apply to this ratio:

 

About 25% of asymptomatic men older than 50 years and PSA values of 4.0-10 ng/mL have prostate cancer, compared with about 12% for those with PSA values of 2.0-3.9 ng/mL. Free PSA can help classify these men into subgroups with higher or lower cancer rates:

 

  Free/Total Ratio Cancer Rate
     

PSA 4.0-10 ng/mL

<0.10 >40%
  >0.25 <10%
PSA 2.0-3.9 ng/mL <0.10 >30%
   >0.18  <10%

Serum markers are not specific for malignancy, and values may vary by method.

Day(s) Test Set Up

Monday through Sunday

Test Classification and CPT Coding

84153-PSA, total

84154-PSA, free