Test Code PSATF Prostate-Specific Antigen (PSA), Total and Free, Serum
Specimen Requirements
Specimen must arrive within 24 hours of draw.
Container/Tube: Gold-top serum gel tube
Specimen Volume: 0.5 mL of serum
Transport Temperature: Refrigerate
Collection Instructions: Forward promptly.
Note: Medicare frequency limitations exist for this test in addition to diagnosis requirements. Click on link for list of medically necessary diagnoses: http://www.munsonhealthcare.org/medical-necessity. See Advance Beneficiary Notice of Noncoverage (ABN) form in Special Instructions.
Performing Laboratory
Munson Healthcare Laboratories
Methodology
Immunoenzymatic Assay
Reference Values
None available for PSA, free. PSA, free is reported as a percentage of PSA, total, the following reference ranges apply to this ratio:
About 25% of asymptomatic men older than 50 years and PSA values of 4.0-10 ng/mL have prostate cancer, compared with about 12% for those with PSA values of 2.0-3.9 ng/mL. Free PSA can help classify these men into subgroups with higher or lower cancer rates:
| Free/Total Ratio | Cancer Rate | |
|
PSA 4.0-10 ng/mL |
<0.10 | >40% |
| >0.25 | <10% | |
| PSA 2.0-3.9 ng/mL | <0.10 | >30% |
| >0.18 | <10% |
Serum markers are not specific for malignancy, and values may vary by method.
Day(s) Test Set Up
Monday through Sunday
Test Classification and CPT Coding
84153-PSA, total
84154-PSA, free