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Test Code P2Y12 P2y12 Platelet Inhibition

Important Note

Direct patients to a hospital outpatient laboratory for collection.  See special instructions for specimen collection and handling.

EHR Test Codes

  Test Code Test Name
Atlas P2Y12 P2Y12 Platelet Inhibition
Cerner   P2Y12 Platelet Inhibition

 

Specimen Requirements

Preparation of Patient:

None

 

Container Type: 

2.0 mL Greiner Bio-One Vacuette Light Blue Top 3.2% Sodium Citrate Tube

Specimen Type:

3.2% Sodium Citrate Whole Blood

 

Specimen Volume:  

2.0 mL

 

Special Collection Instructions:

   Venipuncture:

  1. Collect and discard 4.5 mL whole blood in a blue top tube prior to specimen collection.  Mark tube(s) as WASTE.
  2. Fill Greiner Bio-One Vacuette tube to the black arrow. Do not overfill or underfill.
  3. Mix by inversion at least 5 times.
  4. Label all tubes with two positive patient identifiers per policy.  Place WASTE tube(s) and patient sample in transport bag.

 

   Indwelling Catheter:

  1. Prior to specimen collection, withdraw approximately 5 mL whole blood to clear the indwelling line.  Mark syringe as WASTE.
  2. Inspect line to assure it is free of clots.
  3. Collect blood using either a syringe or vacutainer system, filling the Greiner Bio-One Vacuette tube to the black arrow. Do not overfill or underfill.  When using a syringe, blood must be transferred immediately into the Greiner Bio-One Vacuette tube.
  4. Mix by inversion at least 5 times.
  5. Label all tubes with two positive patient identifiers per policy.  Place WASTE tube(s)/syringe and patient sample in transport bag.

 

Specimen Handling/Transport: 

HAND DELIVER to laboratory.  Do not transport via pneumatic tube.  Transport ambient room temperature. Do not refrigerate, freeze, or centrifuge.

 

Specimen Storage/Stability:

Ambient room temperature 4 hours.

 

Specimen Rejection:

Clotted

Under or over filled tube

Specimen sent through the pneumatic tube

No waste tube drawn

Incorrect tube type drawn

Performing Laboratory

Munson Medical Center Laboratories

Priority, Frequency, & Turnaround

Priority:

STAT, ASAP, Non-Emergent

 

Frequency:

24 hours 7 days a week

 

Turnaround:

0 - 5 hours

STAT 60 minute from receipt in lab

Methodology

Turbidometry

Reporting

Reference Range:

 

Interpretive Data:

P2Y12 Reaction Units
Values less than 180 PRU suggests evidence of a P2Y12 inhibitor effect.

 

Critical Decision:

None

Clinical Significance

The VerifyNow system detects platelet activity by measuring in vitro platelet aggregation in a blood sample exposed to specific agonists. This includes inhibition of platelet activity in response to antiplatelet therapies. Patients given antiplatelet therapy such P2Y12 inhibitors (Ticagrelor, Clopidogrel, Prasugrel) or patients using aspirin can be tested on the VerifyNow system.

CPT Code(s)

85576

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