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Test Code MAMMX 6-Monoacetylmorphine (6-MAM) Confirmation, Chain of Custody, Meconium

Useful For

Detection of in utero drug exposure up to 5 months before birth

 

Chain of custody is required whenever the results of testing could be used in a court of law. Its purpose is to protect the rights of the individual contributing the specimen by demonstrating that it was under the control of personnel involved with testing the specimen at all times; this control implies that the opportunity for specimen tampering would be limited. Since the evidence of illicit drug use during pregnancy can be cause for separating the baby from the mother, a complete chain-of-custody ensures that the test results are appropriate for legal proceedings.

Additional Tests

Test ID Reporting Name Available Separately Always Performed
COCH Chain of Custody Processing No Yes

Reporting Name

6-MAM Confirmation, CoC, M

Specimen Type

Meconium


Shipping Instructions


The laboratory recommends sending chain-of-custody specimens by overnight shipment.



Specimen Required


Supplies: Chain-of-Custody Meconium Kit (T653) includes the specimen containers, seals, and documentation required.

Specimen Volume: 1 g (approximately 1 teaspoon)

Collection Instructions: Collect entire random meconium specimen.

Additional Information: Specimen that arrives with a broken seal does not meet the chain of custody requirements.


Specimen Minimum Volume

0.3 g (approximately 1/4 teaspoon)

Specimen Stability Information

Specimen Type Temperature Time Special Container
Meconium Frozen 14 days

Reject Due To

Hemolysis NA
Lipemia NA
Icterus NA
Other Grossly bloody reject; Pink OK

Reference Values

Negative

Positives are reported with a quantitative LC-MS/MS result.

Cutoff concentration:

6-MAM by LC-MS/MS: 5 ng/g

Day(s) and Time(s) Performed

Monday through Sunday; Varies

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

80356

G0480 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
MAMMX 6-MAM Confirmation, CoC, M 29345-6

 

Result ID Test Result Name Result LOINC Value
36202 6-Monoacetylmorphine 29345-6
36203 Interpretation 69050-3
36204 Chain of Custody 77202-0

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Forms

Chain-of-Custody Request is included in the Chain-of-Custody Kit (T282).