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HelpTest Code LH Lutenizing Hormone
EHR Test Codes
| Test Code | Test Name | |
| Atlas | LH | Lutenizing Hormone |
| Cerner | Lutenizing Hormone |
Specimen Requirements
Preparation of Patient:
None
Container Type:
Green Top 5mL Lithium Heparin Separator Tube
Or
Gold Top 6mL SST Gel & Clot Activator Tube
Specimen Type:
Plasma or Serum
Specimen Volume:
2.5 mL Plasma or Serum minimum .5 mL
Specimen Handling/Transport:
Separate plasma or serum from cells within 2 hours of collection.
Transport ambient room temperature.
Specimen Stability/Storage:
1 day refrigerated 2-8°C
>1 day frozen -20°C
Specimen Rejection:
Gross hemolysis
Performing Laboratory
Munson Medical Center Laboratories
Chemistry Department
Priority, Frequency, & Turnaround
Priority:
Non-Emergent
Frequency:
24 hours 7 days a week
Turnaround:
0 - 1 days
Methodology
Chemiluminescent Immunoassay
Reporting
Reference Range:
Adult Men: 1.8-8.6 IU/L Women: Follicular Phase 2.1-10.9 IU/L Mid-Cycle Peak 20.0-100.0 IU/L Luteal Phase 1.2-12.9 IU/L Postmenopausal 10.0-60.0 IU/L Prepubertal children: <10.0 IU/L
Critical Decision:
None
Clinical Significance
Luteinizing hormone (LH) together with FSH is secreted by the gonadotroph cells in the pituitary in response to gonadotropin releasing hormone from the hypothalamus.
Ovarian steroids, principally estrogens, control the secretion of LH and FSH which, in turn, regulate the female menstrual cycle. When the follicle and ovum within are mature, a surge of LH causes the follicle to rupture releasing the ovum.
During follicular and luteal phases, LH values are lower (estrogens exert a negative feedback on LH release). Before mid-cycle surge of LH, estradiol exerts a positive feedback on LH release/ LH levels are used to predict ovulation in the evaluation of infertility and diagnosis of pituitary and gonadal disorders.
At menopause, LH levels increase due to loss of negative feedback
In males the primary role of LH is to stimulate production of testosterone.
In sexually mature adults, low concentration of LH are observed in panhypopituitarism, delayed puberty, anorexia nervosa, and in females, post- pregnancy.
Elevated LH levels may be due to tumors of the hypothalamus and pituitary.
Gonadal failure is indicated by elevated concentrations of LH and FSH. In females, it may indicate primary amenorrhea, menopause, premature ovarian failure or polycystic ovary. In males, elevated levels can result from testicular failure, Klinefelter's syndrome or anorchia.
CPT Code(s)
83002