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HelpTest Code LEVT Levetiracetam Level
EHR Test Codes
| Test Code | Test Name | |
| Atlas | LEVT | Levetiracetam Level |
| Cerner | Levetiracetam Level |
Specimen Requirements
Preparation of Patient:
Draw immediately before next dose.
Container Type:
Red Top 6mL CAT Serum Clot Activator Tube
Specimen Type:
Serum
Specimen Volume:
2.5 mL Serum minimum .5 mL
Specimen Handling/Transport:
Separate serum from cells within 2 hours of collection.
Transport ambient room temperature.
Specimen Stability/Storage:
5 days refrigerated 2-8°C
Performing Laboratory
Munson Medical Center Laboratories
Chemistry Department
Priority, Frequency, & Turnaround
Priority:
STAT, ASAP, Non-Emergent
Frequency:
24 hours 7 days a week
Turnaround:
0 - 1 days
STAT 60 minute from receipt in lab
Methodology
Homogeneous Enzyme Immunoassay
Reporting
Reference Range:
6 - 46 ug/dL
Interpretive Data:
Patients on Brivaracetam may have a falsely elevated result.
Critical Decision:
none
Clinical Significance
Levetiracetam is approved for the treatment of partial, myoclonic, and tonic-clonic seizures, and is used off-label for manic states and migraine prophylaxis. It has very favorable pharmacokinetics with good bioavailability and rapid achievement of steady state. Levetiracetam is excreted renally, with a mean half-life of 7 hours. Renal dysfunction may warrant therapeutic monitoring and/or dose adjustment. Toxicities include decreased hematocrit and RBC count, decreased neutrophil count, somnolence, asthenia, and dizziness. These toxicities may be associated with blood concentration in the therapeutic range.
CPT Code(s)
80299