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Test Code IGE Immunoglobulin E 

EHR Test Codes

  Test Code Test Name
Atlas IGE IgE, TOTAL
Cerner   Immunoglobulin E

Specimen Requirements

Preparation of Patient: 

None.

 

Container Type: 

Gold Top 6mL SST Gel & Clot Activator Tube

Specimen Type:

Serum

 

Specimen Volume: 

2.5 mL Serum minimum .5 mL

 

Specimen Handling/Transport:

Separate plasma or serum from cells within 2 hours of collection.

Transport refrigerated 2 - 8°C 

 

Specimen Stability/Storage:

8 hours ambient room temperature

5 days refrigerated 2-8°C

Performing Laboratory

Munson Medical Center Laboratories

Chemistry Department

Priority, Frequency, & Turnaround

Priority:

Non-Emergent

 

Frequency:

24 hours 7 days a week

 

Turnaround:

0 - 1 days

Methodology

Immunoturbidimetric

Reporting

Reference Range:

0 years to 7 years 0 - 440 IntlUnit/mL
7 years to 19 years 0 - 450 IntlUnit/mL
19 years and up 0 - 160 IntlUnit/mL

 

Critical Decision: 

none

Clinical Significance

IgE is a member of the immunoglobulin family of proteins. IgE, like all immunoglobulins, is produced by plasma cells in response to antigenic stimuli. IgE is unique however in certain structural aspects and the role it plays in allergic diseases.

 

Measurement of total serum IgE is often used as a tool in the diagnosis and management of atopic diseases such as asthma, allergic rhinitis, atopic dermatitis and urticaria. It has been used to distinguish atopic from non-atopic individuals presenting allergy-like symptoms. In addition, studies have also shown that increased levels of IgE in cord blood and infants may be predictive of future atopic tendencies.

 

Normal levels of circulating IgE are extremely low in comparison to other immunoglobulins. Levels of IgE at birth are almost undetectable but increase in non-allergic adults. Elevated levels are commonly seen in cases of allergic diseases, parasitic infections, pulmonary aspergillosis, and hyper-IgE syndrome.

 

Serum IgE levels may vary as a result of diet, genetic background, geographical location and other factors. It is therefore recommended that total IgE measurements be used in conjunction with other clinical tests when establishing diagnoses.

CPT Code(s)

82785