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Test Code DBS1 Diabetes Mellitus Type 1 Evaluation, Serum

Useful For

Distinguishing type 1 from type 2 diabetes mellitus

 

Identifying individuals at risk of type 1 diabetes (including high-risk relatives of patients with diabetes)

 

Predicting future insulin requirement treatment in patients with adult-onset diabetes

Profile Information

Test ID Reporting Name Available Separately Always Performed
DMEI Diabetes Interpretation, S No Yes
GD65S GAD65 Ab Assay, S Yes Yes
INAB Insulin Abs, S Yes Yes
IA2 IA-2 Ab, S Yes Yes
EZNT8 ZnT8 Ab, S Yes Yes

Method Name

GD65S, INAB, IA2: Radioimmunoassay (RIA)

EZNT8: Enzyme-Linked Immunosorbent Assay (ELISA)

DMEI: Interpretive Comments

Reporting Name

Diabetes Mellitus Type 1 Evaluation

Specimen Type

Serum


Specimen Required


Container/Tube: 

Preferred: Red top

Acceptable: Serum gel

Specimen Volume: 4 mL


Specimen Minimum Volume

2 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  72 hours

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject

Reference Values

GLUTAMIC ACID DECARBOXYLASE (GAD65) ANTIBODY

≤0.02 nmol/L

Reference values apply to all ages.

 INSULIN ANTIBODIES

≤0.02 nmol/L

Reference values apply to all ages.

 ISLET ANTIGEN 2 (IA-2) ANTIBODY

≤0.02 nmol/L

Reference values apply to all ages.

ZINC Transporter 8 (ZnT8) ANTIBODY

< 15.0 U/mL

Reference values apply to all ages.

Day(s) and Time(s) Performed

Monday through Thursday, Sunday; 10 p.m.

GAD65 antibody: Monday through Friday; 4 a.m.; 4 p.m.

Insulin antibodies: Monday, Wednesday, Friday; 4 a.m.

IA-2 antibody: Tuesday, Thursday; 4 a.m.

Zinc Transporter 8 Antibody: Tuesday and Thursday, 10 a.m.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

See Individual Components

CPT Code Information

86337-Insulin antibodies

86341 x3-Islet cell antibody

LOINC Code Information

Test ID Test Order Name Order LOINC Value
DBS1 Diabetes Mellitus Type 1 Evaluation In Process

 

Result ID Test Result Name Result LOINC Value
81596 GAD65 Ab Assay, S 30347-9
89588 IA-2 Ab, S 81155-4
8666 Insulin Abs, S 60463-7
34268 Diabetes Interpretation, S 69048-7
64926 ZnT8 Ab, S 76651-9