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Test Code CRCL Creatinine Clearance

Important Note

Patient height and weight are required order prompts.

EHR Test Codes

  Test Code Test Name
Atlas CRCL Creatinine Clearance
Cerner   Creatinine Clearance

Specimen Requirements

Plasma or serum and 24 hour urine are required. Blood specimen must be drawn within 72 hours before or after urine collection.  Patient height and weight are required on container label and or laboratory requisition.

 

Preparation of Patient: 

None.

 

24 Hour Urine Specimen Collection Instructions:

  1. It is recommended you begin the 24 hour urine collection in the morning.
  2. At the time you choose to start the collection, urinate into the toilet and flush as usual.  DO NOT SAVE this urine in the jug.  Record this start date and time on the jug label.
  3. For the next 24 hours collect all urine and add to the jug.  Do not urinate directly into the jug if a preservative has been added.
  4. All urine is needed for accurate testing.  If you fill the jug, continue the collection into any clean, dry, leak proof container.  Call the labroatory for instructions if you have omitted or spilled any urine 231-935-6100 prompt 4.
  5. Keep the jug refrigerated during the entire collection.  Refrigerate or store in a cooler with ice.
  6. Exactly 24 hours after th start time, urinate and ADD this last urine sample to the jug.  Record this end date and time on the jug label.  Collection is completed.
  7. Within 3 hours or less of completing the collection, deliver the jug and your lab order to the laboratory (preferably a hospital laboratory).  Keep the jub cool during transport.

 

Container Type: 

Green Top 5mL Lithium Heparin Separator Tube

Or

 

Gold Top 6mL SST Gel & Clot Activator Tube

AND

 

24 Hour Urine Container without preservative

 

 

or

 

White Top 6mL No Additive Tube

 

Specimen Type:

Plasma or Serum 

AND

24 hour Urine without preservative

 

Specimen Volume: 

2.5 mL Plasma or Serum minimum .5 mL

AND

24 hour Urine minimum .5 mL

Note:  24 Hour urine volume required on container.

 

Specimen Handling/Transport:

Plasma or Serum:

Separate plasma or serum from cells within 2 hours of collection.

Transport ambient room temperature or refrigerated 2 - 8°C

 

24 Hour Urine:

Transport refrigerated 2 - 8°C.

 

MHC Laboratories:  Mix urine and aliquot into White Top 6ml No Additive Tube via urine transfer straw. Record total volume, patient height, and patient height on container label. Transport refrigerated 2-8°C.

 

Specimen Stability/Storage:

5 days refrigerated 2-8°C

Performing Laboratory

Munson Medical Center Laboratories

Chemistry Department

Priority, Frequency, & Turnaround

Priority:

Non-Emergent

 

Frequency:

24 hours 7 days a week

 

Turnaround:

0 - 1 days

Methodology

Modified Jaffe, Kinetic

Reporting

Reference Range:

Males:

0 Years to 30 Years  92 - 150  mL/min 
30 Years to 40 Years  85 - 143  mL/min 
40 Years to 50 Years  78 - 136  mL/min 
50 Years to 60 Years  72 - 130  mL/min 
60 Years to 70 Years  65 - 123  mL/min 
70 Years to 80 Years  58 - 116  mL/min 
80 Years and up  53 - 109  mL/min 
 

Females:

0 Years to 30 Years  86 - 140  mL/min 
30 Years to 40 Years  79 - 133  mL/min 
40 Years to 50 Years  73 - 126  mL/min 
50 Years to 60 Years  67 - 121  mL/min 
60 Years to 70 Years  60 - 114  mL/min 
70 Years to 80 Years  54 - 108  mL/min 
80 Years and up  48 - 101  mL/min 

 

Calculation:

Urine creatinine X Volume in mL per min. X 1.73 = mL plasma cleared/min per

                  Plasma creatinine                              A             standard surface area

 

Where:

Urine creatinine = concentration of creatinine in urine

Plasma creatinine = concentration of creatinine in plasma in the same units as for urine

V = Volume of urine flow in mL/min (ml per 24hrs / 1440 = mL per min.)

A = Body surface area in square meters

 

Critical Decision: 

None

Clinical Significance

Urinary creatinine is used as an endogenous substance to measure glomerular filtration rate.

CPT Code(s)

82575