Sign in →

Test Code CMVT CMV, IgG & IgM, Serum

Methodology

Chemiluminescent immunoassay (CLIA)

Specimen Requirements

Preparation of Patient: 

None

 

Specimen Type:

Serum

 

Container Type: 

Gold Top SST Gel & Clot Activator Tube

LIS Container Code = GL

 

Specimen Volume: 

1.0 mL of Serum minimum 400uL of Serum

 

Specimen Handling/Transport:

Separate serum from cells within 2 hours of collection

For shipping, specimens should be maintained at 2-8°C.

 

Specimen Stability/Storage:

2 hours ambient

2 days 2-8°C

Aliquoted samples frozen.  Do not repeatedly freeze/thaw 

Reference Range

Reference Ranges:  Negative

Critical Decision Level:   None

Result Interpretation: Results are expressed as U/mL

U/mL Value

Results

Interpretation

< 0.60 U/mL

Negative

Absence of detectable CMV IgG antibodies.  A negative result generally indicates that immunity has not been acquired.  If Exposure to CMV is suspected despite a negative finding, a second sample should be collected and tested no less than one or tow weeks later.

≥ 0.60 U/mL

and

< 0.70 U/mL

Equivocal

The equivocal sample should be repeat tested.  In case the result remains in the range after repeat testing, as second sample should be collected.

≥ 0.70 U/mL

Positive

Presence of detectable CMV IgG antibodies.  A positive result generally indicates either recent or past exposure to the CMV.

 

Reference Ranges:  Negative

Critical Decision Level:   None

Result Interpretation: Results are expressed as AU/mL

AU/mL Value

Results

Interpretation

< 30.0 AU/mL

Negative

Absence of detectable CMV IgM antibodies.  A negative result, hower, does not always rule out acute hCMV infection.  The IgM response may not be detectable in the very early stage of the infection or if the patient is immunocompromised.  If clinical exposure to hCMV is suspected despite a negative finding, a second sample should be collected and tested no less than one or two weeks later.

≥ 30.0 AU/mL

and

< 35.0 AU/mL

Equivocal

The equivocal sample should be repeat tested.  In case the result remains in the range after repeat testing, as second sample should be collected.

≥ 35.0 AU/mL

Positive

Presence of detectable CMV IgM antibodies.  A positive result generally indicative of acute infection, reactivation or persistent IgM production.

 

Note:  The presence of CMV IgM should also be determined to assess the stage of CMV infection. Diagnosis of infectious diseases should not be established on the basis of a single test result, but should be determined in conjunction with clinical findings and other diagnostic procedures as well as in association with medical judgment.  Diseases such as Epstein-Barr viral syndrome, toxoplasmosis and hepatitis may cause symptoms similar to CMV infection and must be excluded before confirmation of diagnosis.

Test Classification and CPT Coding

86644

86645

Test Priority & Frequency

Non-Emergent

Monday and Thursday