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Test Code APGH Alpha-Subunit Pituitary Tumor Marker, Serum

Reporting Name

AlphaSubunit Pituitary Tumor Marker

Useful For

Adjunct in the diagnosis of pituitary tumors

 

As part of the follow-up of treated pituitary tumor patients

 

Differential diagnosis of thyrotropin-secreting pituitary tumor versus thyroid hormone resistance

 

Differential diagnosis of constitutional delay of puberty versus hypogonadotrophic hypogonadism

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum


Ordering Guidance


This test should not be ordered on pregnant patients.



Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial


Specimen Minimum Volume

0.35 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Frozen (preferred) 90 days
  Refrigerated  7 days

Reference Values

PEDIATRIC

≤5 days: ≤50 ng/mL

6 days-12 weeks: ≤10 ng/mL

3 months-17 years: ≤1.2 ng/mL

Tanner II-IV*: ≤1.2 ng/mL

 

ADULTS

Males: ≤0.5 ng/mL

Premenopausal females: ≤1.2 ng/mL

Postmenopausal females: ≤1.8 ng/mL

 

Pediatric and adult reference values based on Mayo studies.

 

*Puberty onset (transition from Tanner stage I to Tanner stage II) occurs for boys at a median age of 11.5 (±2) years and for girls at a median age of 10.5 (±2) years. There is evidence that it may occur up to 1 year earlier in obese girls and in African American girls. For boys, there is no proven relationship between puberty onset and body weight or ethnic origin. Progression through Tanner stages is variable. Tanner stage V (adult) should be reached by age 18.

Day(s) Performed

Sunday

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

82397

LOINC Code Information

Test ID Test Order Name Order LOINC Value
APGH AlphaSubunit Pituitary Tumor Marker 14170-5

 

Result ID Test Result Name Result LOINC Value
9003 AlphaSubunit Pituitary Tumor Marker 14170-5

Report Available

2 to 8 days

Reject Due To

Gross hemolysis Reject
Gross lipemia OK
Gross icterus OK

Method Name

Immunochemiluminescent Assay

Forms

If not ordering electronically, complete, print, and send an Oncology Test Request (T729) with the specimen.