Test Code APGH Alpha-Subunit Pituitary Tumor Marker, Serum
Specimen Required
Collection Container/Tube: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Forms
If not ordering electronically, complete, print, and send an Oncology Test Request (T729) with the specimen.
Useful For
Adjunct in the diagnosis of pituitary tumors
As part of the follow-up of treated pituitary tumor patients
Differential diagnosis of thyrotropin-secreting pituitary tumor versus thyroid hormone resistance
Differential diagnosis of constitutional delay of puberty versus hypogonadotrophic hypogonadism
Method Name
Immunochemiluminescent Assay
Reporting Name
AlphaSubunit Pituitary Tumor MarkerSpecimen Type
Serum RedSpecimen Minimum Volume
0.35 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Serum Red | Frozen (preferred) | 90 days | |
Refrigerated | 7 days |
Reject Due To
Gross hemolysis | Reject |
Gross lipemia | OK |
Gross icterus | OK |
Reference Values
PEDIATRIC
≤5 days: ≤50 ng/mL
6 days-12 weeks: ≤10 ng/mL
3 months-17 years: ≤1.2 ng/mL
Tanner II-IV*: ≤1.2 ng/mL
ADULTS
Males: ≤0.5 ng/mL
Premenopausal females: ≤1.2 ng/mL
Postmenopausal females: ≤1.8 ng/mL
Pediatric and adult reference values based on Mayo studies.
*Puberty onset (transition from Tanner stage I to Tanner stage II) occurs for boys at a median age of 11.5 (±2) years and for girls at a median age of 10.5 (±2) years. There is evidence that it may occur up to 1 year earlier in obese girls and in African American girls. For boys, there is no proven relationship between puberty onset and body weight or ethnic origin. Progression through Tanner stages is variable. Tanner stage V (adult) should be reached by age 18.
Day(s) and Time(s) Performed
Wednesday; 10 a.m.
Performing Laboratory

Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.CPT Code Information
82397
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
APGH | AlphaSubunit Pituitary Tumor Marker | 14170-5 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
9003 | AlphaSubunit Pituitary Tumor Marker | 14170-5 |