Test Name ALT Alanine aminotransferase
Specimen Requirements
Preparation of Patient:
None
Container Type:
Gold Top 6mL SST Gel & Clot Activator Tube
Or
Green Top 5mL Lithium Heparin Separator Tube
Specimen Type:
Serum or Plasma
Specimen Volume:
2.5 mL Serum or Plasma
minimum .5 mL of Serum or Plasma
Specimen Handling/Transport:
Separate serum or plasma from cells within 2 hours of collection.
Transport ambient room temperature.
Specimen Stability/Storage:
5 days refrigerated 2-8°C
Performing Laboratory
Munson Healthcare Laboratories
Priority, Frequency, & Turnaround
Priority:
STAT, ASAP, Non-Emergent
Frequency:
24 hours 7 days a week
Turnaround:
0 - 1 days
STAT 60 minute from receipt in lab
Methodology
Enzymatic Rate Reaction L-alanine to pyruvate
Reporting
Reference Range:
Males: 7-55 U/L
Females: 7-38 U/L
Linearity Range:
3 - 10,000 U/L
Critical Decision:
Pediatric patients up to 21 years old ≥ 150 IU/L
Note: Critical values are called to the provider and communicated as critical. Documentation of the call is recorded in the patient record.
Clinical Significance
Significant elevations of ALT occur only in disease of the liver. ALT is often measured in conjunction with AST to determine whether the source of elevated AST is liver or the heart.
CPT Code(s)
84460