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HelpTest Code ABOA1B Apolipoprotein A1 and B with Ratio
EHR Test Codes
| Test Code | Test Name | |
| Atlas | APOA1B | Apolipoprotein A1 and B with Ratio |
| Cerner | Apolipoprotein A1 and B with Ratio |
Specimen Requirements
Preparation of Patient:
Fasting is preferred but not required unless specified by ordering provider.
Container Type:
Gold Top 6mL SST Gel & Clot Activator Tube
Specimen Type:
Serum
Specimen Volume:
2.5 mL Serum minimum .5 mL
Specimen Handling/Transport:
Transport ambient room temperature or refrigerated 2 - 8°C.
Specimen Stability/Storage:
24 hours ambient room temperature
5 days refrigerated 2-8°C
Specimen Rejection:
Moderate Hemolysis
Gross Lipemia
Performing Laboratory
Munson Medical Center Laboratories
Chemistry Department
Priority, Frequency, & Turnaround
Priority:
Non-Emergent
Frequency:
24 hours 7 days a week
Turnaround:
0 - 1 days
Methodology
Immunoturbidimetric
Reporting
Reference Range:
Apolipoprotein A1 Male ≥120 mg/dL Female ≥140 mg/dL
Apolipoprotein B < 90 mg/dL
Apolipoprotein B/A1 ratio <0.6 Lower risk; 0.6-0.8 Average risk; >0.8 High risk
Critical Decision:
None
Clinical Significance
Lipids are transported throughout the body by complex structures called lipoproteins. Lipoproteins are classified into five major density classes: chylomicrons, very low density lipoprotein (VLDL), intermediate density lipoprotein (IDL), low density lipoprotein (LDL) and high density lipoprotein (HDL). Over the past several decades, decreased serum levels of high density lipoprotein (HDL) and increased levels of low density lipoprotein (LDL) have been associated with increased risk of coronary artery disease.
Associated with these lipoproteins, at least five major apolipoproteins have been described and have been labeled A through E. Apo A1 plays a role in the activation of lecithin-cholesterol-acyltransferase (LCAT) and removal of free cholesterol from extrahepatic tissues. Apolipoprotein B (Apo B) is the major protein component of VLDL and LDL, and therefore plays an essential role in lipid transport and metabolism.
Apolipoprotein B/Apolipoprotein A1 ratio measures the balance between pro-atherogenic particles and anti-atherogenic particles in the blood. A high ratio indicated elevated cardiovascular and metabolic risk.
CPT(s)
82172 x 2