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Test Code A1M24 Alpha-1-Microglobulin, 24 Hour, Urine

Reporting Name

Alpha-1-Microglobulin, 24-Hour, U

Useful For

Assessment of renal tubular injury or dysfunction

 

Screening for tubular abnormalities

 

Detecting chronic asymptomatic renal tubular dysfunction(2)

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Urine


Specimen Required


Container/Tube: Plastic, 5-mL tube

Specimen Volume: 4 mL

Collection Instructions:

1. Collect urine for 24 hours.

2. No preservative.

3. Mix well before taking 4-mL aliquot.

Additional Information:

1. 24-Hour volume is required.

2. See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens in Special Instructions for multiple collections.


Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 7 days
  Ambient  7 days
  Frozen  7 days

Reference Values

≥16 years: <19 mg/24 hours

7 mg/g creatinine is a literature suggested upper reference limit for pediatrics 1 month to 15 years of age.*

 

*Hjorth L, Helin I, Grubb A: Age-related reference limits for protein HC in children. Scand J Clin Lab Invest 2000 Feb;60(1):65-73

Day(s) and Time(s) Performed

Varies; 8 a.m. to 4 p.m.

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

83883

LOINC Code Information

Test ID Test Order Name Order LOINC Value
A1M24 Alpha-1-Microglobulin, 24-Hour, U 48414-7

 

Result ID Test Result Name Result LOINC Value
AIM Alpha-1-Microglobulin, 24-Hour, U 48414-7
A1MCR A1M/Creat Ratio 48415-4
DUR5 Collection Duration 13362-9
VL58 Urine Volume 3167-4
A1MC Alpha-1-Microglobulin Concentration 46723-3
CR_C Creatinine Concentration 20624-3

Reject Due To

Gross hemolysis Reject

Method Name

Immunonephelometry

Urine Preservative Collection Options

Note: The addition of preservative or application of temperature controls must occur within 4 hours of completion of the collection.

Ambient

Yes

Refrigerate

Preferred

Frozen

Yes

50% Acetic Acid

Yes

Boric Acid

Yes

Diazolidinyl Urea

No

6M Hydrochloric Acid

No

6M Nitric Acid

No

Sodium Carbonate

No

Thymol

Yes

Toluene

No

Forms

If not ordering electronically, complete, print, and send a Renal Diagnostics Test Request (T830) with the specimen.